Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 10/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049865 | 0.89 | TSHR (0.58) | KIF11TSHRACHELMNAALOX12 | |
| SCHEMBL17336268 | 0.87 | KCNN4 (0.70) | KIF11TSHRACHEKCNN4LMNA | |
| SCHEMBL10806896 | 0.85 | KIF11 (0.50) | KIF11TSHRACHEKCNN4LMNA | |
| SCHEMBL7207081 | 0.83 | KIF11 (0.48) | KIF11TSHRACHEKCNN4LMNA | |
| SCHEMBL15366 | 0.83 | KCNN4 (0.69) | KIF11TSHRKCNN4KMT2A | |
| SCHEMBL28410415 | 0.81 | KIF11 (0.56) | KIF11TSHRACHEKCNN4LMNA | |
| SCHEMBL9632111 | 0.81 | TSHR (0.57) | KIF11TSHRACHEKCNN4LMNA | |
| SCHEMBL14276997 | 0.81 | TSHR (0.57) | KIF11TSHRACHEKCNN4LMNA | |
| SCHEMBL8671538 | 0.81 | TSHR (0.57) | KIF11TSHRACHEKCNN4LMNA | |
| Methyl Alcohol SCHEMBL28720439 | 0.80 | KCNN4 (0.58) | TSHRKCNN4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104396-A1 | Process for preparation of diamines or mixtures of diamines | BAYER AG (DE) | 1984-04-04 | — | — | EP | disclosed |
| EP-0104531-A1 | Cycloaliphatic diisocyanates, possibly in the form of a mixture of isomers, method for their preparation and their use as starting products in the preparation of synthetic products of the polyurethane type | BAYER AG (DE) | 1984-04-04 | — | — | EP | disclosed |