Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | MPL | P40238 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCND3 | P30281 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086899 | 0.89 | APOBEC3A (0.42) | APOBEC3AAPOBEC3GMTNR1AMAPTSMN1; SMN2 | |
| SCHEMBL8188498 | 0.79 | MPL (0.55) | APOBEC3AAPOBEC3GMTNR1AMAPTSMN1; SMN2 | |
| SCHEMBL8838321 | 0.75 | MTNR1A (0.56) | MTNR1ACYP1A2CYP2A6RAB9AKMT2A | |
| SCHEMBL11078414 | 0.74 | IDO1 (0.41) | SMN1; SMN2CYP1A2CYP2A6PLK1NPC1 | |
| SCHEMBL19382614 | 0.72 | CYP1A2 (0.61) | MTNR1AMAPTSMN1; SMN2PLAUCYP1A2 | |
| SCHEMBL12831543 | 0.70 | F10 (0.47) | MAPTF10CYP1A2CYP2A6NPC1 | |
| SCHEMBL20651318 | 0.70 | PLAU (0.43) | APOBEC3AAPOBEC3GMTNR1AMAPTSMN1; SMN2 | |
| SCHEMBL11695914 | 0.70 | KDM4E (0.36) | MAPTSMN1; SMN2POLBRAB9AKMT2A | |
| SCHEMBL10522185 | 0.69 | MEN1 (0.49) | APOBEC3AAPOBEC3GMTNR1AMAPTSMN1; SMN2 | |
| SCHEMBL4789564 | 0.68 | CYP1A2 (0.56) | MTNR1AMAPTSMN1; SMN2PLAUCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435417-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1984-03-06 | — | — | US | disclosed |
| EP-0012866-B1 | NEW 3H-NAPHTHO(1,2-D)IMIDAZOLES, PROCESSES FOR PREPARING THEM, COMPOUNDS FOR USE AS ANTIINFLAMMATORY AND ANTIMICROBIAL AGENTS AND COMPOSITIONS FOR THAT USE CONTAINING THEM | GRUPPO LEPETIT S.P.A. (IT) | 1983-01-19 | — | — | EP | disclosed |
| EP-0012866-A1 | New 3H-naphtho(1,2-d)imidazoles, processes for preparing them, compounds for use as antiinflammatory and antimicrobial agents and compositions for that use containing them | GRUPPO LEPETIT S.P.A. (IT) | 1980-07-09 | — | — | EP | disclosed |