Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 13/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 13/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.49 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085857 | 0.92 | PDE4A (0.47) | CYP1A2CYP11B1CYP11B2PDE4APDE4B | |
| SCHEMBL11094260 | 0.90 | PDE4A (0.50) | CYP1A2CYP11B1CYP11B2PDE4APDE4B | |
| SCHEMBL11086404 | 0.89 | CYP1A2 (0.52) | CYP1A2CYP11B1CYP11B2ATAD2PDE3B | |
| SCHEMBL11079653 | 0.87 | PDE3B (0.48) | CYP1A2CYP11B1CYP11B2PDE4APDE4B | |
| SCHEMBL11094366 | 0.86 | PDE3B (0.62) | CYP1A2CYP11B1CYP11B2PDE4APDE4B | |
| SCHEMBL11090062 | 0.86 | PDE4A (0.46) | CYP1A2CYP11B1CYP11B2PDE4APDE4B | |
| SCHEMBL11090645 | 0.82 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL11093035 | 0.81 | PDE3B (0.65) | CYP1A2CYP11B1CYP11B2PDE4APDE4B | |
| SCHEMBL11084934 | 0.81 | PDE3B (0.48) | CYP1A2CYP11B1CYP11B2ATAD2PDE3B | |
| SCHEMBL11091984 | 0.81 | PDE3B (0.55) | CYP1A2CYP11B1CYP11B2PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474785-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | BASF AKTIENGESELLSCHAFT (DE) | 1984-10-02 | — | — | US | disclosed |