Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879494 | 0.77 | CYP19A1 (0.37) | PTGS1PTGS2MGLLFAAHCYP19A1 | |
| SCHEMBL9231032 | 0.74 | CYP19A1 (0.35) | PTGS1PTGS2MGLLFAAHCYP19A1 | |
| SCHEMBL1164102 | 0.67 | MGLL (0.42) | PTGS1PTGS2MGLLFAAHCYP19A1 | |
| SCHEMBL8414230 | 0.66 | MGLL (0.38) | PTGS1PTGS2MGLLFAAHCYP19A1 | |
| SCHEMBL25033785 | 0.66 | CHRM2 (0.38) | GAAPTGS1PTGS2MGLLFAAH | |
| SCHEMBL9388255 | 0.66 | CYP19A1 (0.37) | SIRT2PTPN1MGLLFAAHCYP19A1 | |
| SCHEMBL17803474 | 0.66 | KDM4E (0.32) | SIRT2PTGS1PTGS2MGLLFAAH | |
| SCHEMBL6077915 | 0.63 | CYP19A1 (0.51) | CYP19A1 | |
| SCHEMBL1472916 | 0.63 | PTGS1 (0.42) | PTGS1PTGS2MGLLFAAHCYP19A1 | |
| SCHEMBL8625738 | 0.62 | SIRT2 (0.42) | SIRT2MGLLFAAHCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042270-B1 | LUBRICATING OIL ADDITIVE, METHOD FOR MAKING THE SAME, LUBRICATING OIL ADDITIVE PACKAGE, AND LUBRICATING OIL COMPOSITION COMPRISING THE SAME, AND THE USE OF CERTAIN SUCCINIMIDES IN FORMING OIL ADDITIVES | EDWIN COOPER INC. (US) | 1984-09-12 | — | — | EP | disclosed |
| US-4325827-A | FRICTION RESISTANCE | EDWIN COOPER, INC. (US) | 1982-04-20 | — | — | US | disclosed |
| EP-0042270-A2 | Lubricating oil additive, method for making the same, lubricating oil additive package, and lubricating oil composition comprising the same, and the use of certain succinimides in forming oil additives | EDWIN COOPER INC. (US) | 1981-12-23 | — | — | EP | disclosed |
| US-4295983-A | Lubricating oil composition containing boronated N-hydroxymethyl succinimide friction reducers | ETHYL CORPORATION (US) | 1981-10-20 | — | — | US | disclosed |