Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11091998 | 0.91 | LMNA (0.49) | MAPTRAB9ANPC1LMNATP53 | |
| SCHEMBL11091891 | 0.89 | LMNA (0.55) | MAPTRAB9ANPC1LMNATP53 | |
| SCHEMBL11084694 | 0.83 | TP53 (0.51) | MAPTRAB9ANPC1LMNATP53 | |
| SCHEMBL11095432 | 0.83 | MAPT (0.50) | MAPTRAB9ANPC1LMNATP53 | |
| SCHEMBL11081454 | 0.82 | TP53 (0.53) | MAPTRAB9ANPC1LMNATP53 | |
| SCHEMBL11093305 | 0.82 | PDGFRB (0.46) | MAPTRAB9ANPC1LMNATP53 | |
| SCHEMBL11090659 | 0.81 | LMNA (0.45) | MAPTRAB9ANPC1LMNATP53 | |
| SCHEMBL11094565 | 0.80 | PDGFRB (0.50) | MAPTRAB9ANPC1LMNATP53 | |
| SCHEMBL11090022 | 0.79 | MAPT (0.47) | MAPTRAB9ANPC1LMNATP53 | |
| SCHEMBL11090510 | 0.79 | PDGFRB (0.55) | MAPTRAB9ANPC1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460773-A | ANTITUMOR AGENTS, VIRICIDES | LION CORPORATION (JP) | 1984-07-17 | — | — | US | disclosed |