Butane

Butane

SCHEMBL11087786

CCCC.CCOC(=O)CCO[PH](=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
GAA P10253 2/20 0.41
MGAM O43451 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
ALDH1A1 P00352 5/20 0.39
TRPA1 O75762 1/20 0.39
DGKA P23743 1/20 0.38
CYP4F2 P78329 2/20 0.36
CYP4A11 Q02928 2/20 0.36
NR1I2 O75469 1/20 0.35
PGR P06401 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
PTGS2 P35354 1/20 0.35
PDE4D Q08499 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
LMNA P02545 3/20 0.34
POLB P06746 2/20 0.34
TSHR P16473 2/20 0.34
TDP1 Q9NUW8 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11583082 0.81 CYP1A2 (0.42) CYP1A2GAAMGAMSIMGAM2
Butane SCHEMBL5481709 0.80 GAA (0.44) CYP1A2GAAMGAMSIMGAM2
Butane SCHEMBL21219383 0.77 ALDH1A1 (0.50) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL3618711 0.75 GAA (0.48) CYP1A2GAAMGAMSIMGAM2
Butane SCHEMBL21219398 0.74 ALDH1A1 (0.46) ALDH1A1TSHR
Butane SCHEMBL21219375 0.74 ALDH1A1 (0.46) CYP1A2GAAMGAMSIMGAM2
Butane SCHEMBL4247130 0.74 TSHR (0.31) TSHR
SCHEMBL1506864 0.74
SCHEMBL12227423 0.73 CYP1A2 (0.42) CYP1A2GAAMGAMSIMGAM2
SCHEMBL11583081 0.73 CYP1A2 (0.39) CYP1A2GAAMGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4436899-A REACTION OF ORGANIC PHOSPHONATE OR PHOSPHATE WITH TETRAVALENT METAL COMPOUND OCCIDENTAL RESEARCH CORPORATION (US) 1984-03-13 US disclosed
EP-0010366-B1 SOLID ORGANOMETALLIC INORGANIC POLYMERS AND THEIR APPLICATION OCCIDENTAL RESEARCH CORPORATION (US) 1983-02-16 EP disclosed
EP-0010857-B1 LAYERED OR AMORPHOUS ORGANOMETALLIC INORGANIC POLYMERS AND THEIR USE OCCIDENTAL RESEARCH CORPORATION (US) 1982-10-20 EP disclosed
US-4298723-A ION EXCHANGERS, CATALYSTS, SORBENTS, CONTROLLED RELEASE, INTERCALATION COMPOUNDS OCCIDENTAL RESEARCH CORPORATION (US) 1981-11-03 US disclosed
US-4256872-A INTERCALATION COMPOUNDS PREPARED BY THE METATHESIS REACTION IN LIQUID PHASE OF AN INORGANIC TETRAVALENT METAL COMPOUND AND AN ORGANIC PHOSPHONATE; ION EXCHANGERS OCCIDENTAL RESEARCH CORPORATION (US) 1981-03-17 US disclosed
US-4235990-A CRYSTALS WHICH DISPLAY INTERCALATION ACTIVITY OR CAN BE AMORPHOUS OCCIDENTAL RESEARCH CORPORATION (US) 1980-11-25 US disclosed
US-4232146-A Process for preparing layered organophosphorus inorganic polymers OCCIDENTAL RESEARCH CORPORATION (US) 1980-11-04 US disclosed
EP-0010857-A2 Layered or amorphous organometallic inorganic polymers and their use OCCIDENTAL RESEARCH CORPORATION (US) 1980-05-14 EP disclosed
EP-0010366-A1 Solid organometallic inorganic polymers and their application OCCIDENTAL RESEARCH CORPORATION (US) 1980-04-30 EP disclosed
WO-1980000703-A1 SOLID ORGANOMETALLIC INORGANIC POLYMERS OCCIDENTAL RES CORP (US) 1980-04-17 WO disclosed
WO-1980000704-A1 LAYERED OR AMORPHOUS ORGANOMETALLIC INORGANIC POLYMERS OCCIDENTAL RES CORP (US) 1980-04-17 WO disclosed