Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 14/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 9/20 | 0.41 |
| ▸ | GABRP | O00591 | 5/20 | 0.40 |
| ▸ | GABRD | O14764 | 5/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.40 |
| ▸ | GABRE | P78334 | 5/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11094132 | 0.92 | PTGS1 (0.46) | PTGS1PTGS2GABRB3GABRA2GABRB2 | |
| SCHEMBL11094611 | 0.90 | PTGS1 (0.42) | PTGS1PTGS2GABRB3GABRA2GABRB2 | |
| SCHEMBL11091276 | 0.89 | GABRP (0.41) | PTGS1PTGS2GABRB3GABRA2GABRB2 | |
| SCHEMBL10848521 | 0.88 | PTGS1 (0.53) | PTGS1PTGS2GABRB3GABRA2GABRB2 | |
| SCHEMBL11091431 | 0.88 | PTGS1 (0.41) | PTGS1PTGS2GABRB3GABRA2GABRB2 | |
| SCHEMBL11094838 | 0.88 | PTGS1 (0.47) | PTGS1PTGS2GABRB3GABRA2GABRB2 | |
| SCHEMBL9458782 | 0.88 | PTGS1 (0.45) | PTGS1PTGS2GFERCYP3A4SMN1; SMN2 | |
| SCHEMBL11089201 | 0.88 | PTGS1 (0.40) | PTGS1PTGS2GABRB3GABRA2GABRB2 | |
| SCHEMBL10618462 | 0.87 | PTGS1 (0.41) | PTGS1PTGS2GABRB3GFER | |
| SCHEMBL11085112 | 0.87 | PTGS1 (0.41) | PTGS1PTGS2GABRB3GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4459150-A | 5-Acylamino-4-cyano-1-phenylpyrazole derivatives and use as herbicides | MAY & BAKER LIMITED (GB) | 1984-07-10 | — | — | US | claimed |