Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | NME2 | P22392 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.43 |
| ▸ | TUBB | P07437 | 3/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11088137 | 1.00 | RAB9A (0.49) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL11090230 | 0.94 | KMT2A (0.54) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL11090232 | 0.94 | KMT2A (0.54) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL11091289 | 0.92 | RAB9A (0.56) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL11091294 | 0.92 | RAB9A (0.56) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL11117916 | 0.90 | MEN1 (0.57) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL11117912 | 0.90 | MEN1 (0.57) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL11091547 | 0.89 | MEN1 (0.49) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL11091438 | 0.89 | MEN1 (0.49) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL11080895 | 0.85 | RAB9A (0.61) | RAB9ANPC1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4428952-A | Substituted pyrrolo[2,1-b]quinazolines and pyrido[2,1-b]quinazolines useful for the treatment of or the prevention of gastrointestinal ulcers | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-01-31 | — | — | US | disclosed |