Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.44 |
| ▸ | PDE4A | P27815 | 3/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.44 |
| ▸ | BRD4 | O60885 | 4/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.35 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.34 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.32 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093424 | 0.89 | HRH3 (0.43) | HRH3PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL11086367 | 0.81 | GPR119 (0.45) | HRH3PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL11092766 | 0.81 | MAPT (0.49) | HRH3PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL11084831 | 0.79 | PDE4A (0.51) | HRH3PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL11083063 | 0.79 | HRH3 (0.43) | HRH3PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL11091160 | 0.78 | TRIM24 (0.48) | HRH3PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL11088961 | 0.77 | PDE4A (0.55) | HRH3PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL11087147 | 0.77 | PDE3B (0.54) | HRH3PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL11086020 | 0.76 | PDE3B (0.43) | HRH3PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL11082375 | 0.76 | PDE3B (0.47) | HRH3PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474785-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | BASF AKTIENGESELLSCHAFT (DE) | 1984-10-02 | — | — | US | disclosed |