Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085115 | 1.00 | POLB (0.47) | POLBPOLA1CTSKDGKATSHR | |
| SCHEMBL28633231 | 1.00 | POLB (0.47) | POLBPOLA1CTSKDGKATSHR | |
| SCHEMBL403548 | 1.00 | POLB (0.47) | POLBPOLA1CTSKDGKATSHR | |
| SCHEMBL17678892 | 1.00 | POLB (0.47) | POLBPOLA1CTSKDGKATSHR | |
| SCHEMBL11085114 | 1.00 | POLB (0.47) | POLBPOLA1CTSKDGKATSHR | |
| SCHEMBL15167017 | 1.00 | POLB (0.47) | POLBPOLA1CTSKDGKATSHR | |
| SCHEMBL13450360 | 1.00 | POLB (0.47) | POLBPOLA1CTSKDGKATSHR | |
| SCHEMBL15167195 | 1.00 | POLB (0.47) | POLBPOLA1CTSKDGKATSHR | |
| SCHEMBL15167015 | 1.00 | POLB (0.47) | POLBPOLA1CTSKDGKATSHR | |
| SCHEMBL737124 | 0.95 | PRKCA (0.45) | POLBPOLA1CTSKDGKATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469705-A | HYDROXYTHIOETHER FATTY ACID DERIVATIVES | MCNEILAB, INC. (US) | 1984-09-04 | — | — | US | disclosed |
| US-4461775-A | ANTIALLERGENS, ANTIASTHMATIC AGENTS | MCNEILAB, INC. (US) | 1984-07-24 | — | — | US | disclosed |