Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18095730 | 0.81 | ALDH1A1 (0.59) | ALDH1A1RXFP1NPSR1KDM4EMEN1 | |
| SCHEMBL9442885 | 0.80 | ALDH1A1 (0.58) | ALDH1A1RXFP1NPSR1KDM4EMEN1 | |
| SCHEMBL11082680 | 0.80 | ALDH1A1 (0.50) | ALDH1A1RXFP1NPSR1KDM4EMEN1 | |
| SCHEMBL11090971 | 0.78 | KDM4E (0.65) | ALDH1A1NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL10339532 | 0.78 | ALDH1A1 (0.48) | ALDH1A1RXFP1NPSR1KDM4EMEN1 | |
| SCHEMBL18106121 | 0.76 | MAPT (0.66) | ALDH1A1RXFP1NPSR1KDM4EMEN1 | |
| SCHEMBL620812 | 0.76 | KDM4E (0.57) | ALDH1A1RXFP1NPSR1KDM4EMEN1 | |
| SCHEMBL5451976 | 0.75 | KDM4E (0.54) | ALDH1A1RXFP1NPSR1KDM4EMEN1 | |
| SCHEMBL18952941 | 0.74 | ALDH1A1 (0.51) | ALDH1A1RXFP1NPSR1KDM4EMEN1 | |
| SCHEMBL11697805 | 0.73 | NPSR1 (0.47) | ALDH1A1RXFP1NPSR1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472404-A | BACTERICIDES, FUNGICIDES; UROGENITAL DISORDERS | THE DOW CHEMICAL COMPANY (US) | 1984-09-18 | — | — | US | claimed |
| US-4472404-A | BACTERICIDES, FUNGICIDES; UROGENITAL DISORDERS | THE DOW CHEMICAL COMPANY (US) | 1984-09-18 | — | — | US | disclosed |