Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092619 | 0.92 | ACHE (0.40) | ALDH1A1MEN1KMT2AL3MBTL1ACHE | |
| SCHEMBL10982389 | 0.81 | TP53 (0.43) | ALDH1A1MEN1KMT2AL3MBTL1TP53 | |
| SCHEMBL10985156 | 0.81 | TP53 (0.43) | ALDH1A1MEN1KMT2AL3MBTL1TP53 | |
| SCHEMBL10986399 | 0.81 | TP53 (0.43) | ALDH1A1MEN1KMT2AL3MBTL1TP53 | |
| SCHEMBL10984785 | 0.81 | TP53 (0.43) | ALDH1A1MEN1KMT2AL3MBTL1TP53 | |
| SCHEMBL10992398 | 0.81 | TP53 (0.43) | ALDH1A1MEN1KMT2AL3MBTL1TP53 | |
| SCHEMBL10986404 | 0.81 | TP53 (0.43) | ALDH1A1MEN1KMT2AL3MBTL1TP53 | |
| SCHEMBL10992428 | 0.81 | TP53 (0.43) | ALDH1A1MEN1KMT2AL3MBTL1TP53 | |
| SCHEMBL10982382 | 0.81 | TP53 (0.43) | ALDH1A1MEN1KMT2AL3MBTL1TP53 | |
| SCHEMBL10987410 | 0.81 | TP53 (0.43) | ALDH1A1MEN1KMT2AL3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042298-B1 | INDOLE AND INDOLINE DERIVATIVES | MAY & BAKER LIMITED (GB) | 1984-09-12 | — | — | EP | claimed |