Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18279522 | 1.00 | LMNA (0.55) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL28186220 | 1.00 | LMNA (0.55) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL18279501 | 1.00 | LMNA (0.55) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL18279536 | 1.00 | LMNA (0.55) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL6220049 | 0.98 | SMN1; SMN2 (0.52) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11449115 | 0.91 | LMNA (0.48) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL18279514 | 0.91 | LMNA (0.48) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL3841950 | 0.91 | LMNA (0.48) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL18279512 | 0.91 | LMNA (0.48) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL18279534 | 0.91 | LMNA (0.48) | LMNAALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050327-B1 | PHOSPHOLIPIDS THAT CONTAIN SULPHUR, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1984-06-20 | — | — | EP | disclosed |
| US-4444766-A | ANTITUMOR | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-24 | — | — | US | disclosed |
| EP-0050327-A1 | Phospholipids that contain sulphur, process for their preparation and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1982-04-28 | — | — | EP | disclosed |