Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL11088676 | 0.99 | AKR1C3 (0.41) | ALDH1A1LMNAMAPTL3MBTL1BAZ2B | |
| SCHEMBL11088975 | 0.76 | HPGD (0.57) | ALDH1A1LMNAMAPTL3MBTL1BAZ2B | |
| Iodide SCHEMBL11095727 | 0.74 | AKR1C3 (0.38) | ALDH1A1LMNAMAPTL3MBTL1BAZ2B | |
| SCHEMBL11182694 | 0.74 | HSD17B10 (0.52) | ALDH1A1LMNAMAPTL3MBTL1HSD17B10 | |
| SCHEMBL11090997 | 0.73 | KDM4E (0.47) | ALDH1A1LMNAMAPTL3MBTL1HSD17B10 | |
| Hydrochloric Acid SCHEMBL11089322 | 0.72 | KDM4E (0.46) | ALDH1A1LMNAMAPTL3MBTL1HSD17B10 | |
| SCHEMBL11744562 | 0.70 | KDM4E (0.41) | ALDH1A1LMNAMAPTAKR1C3AKR1C2 | |
| SCHEMBL4129093 | 0.70 | KDM4E (0.48) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL4129090 | 0.70 | KDM4E (0.48) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL4131419 | 0.69 | KDM4E (0.54) | ALDH1A1LMNAMAPTAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482557-A | 3-Substituted-2-oxo-tetrahydro-pyrrol[1,2-a]pyrimidines having digitalis-like activity | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1984-11-13 | — | — | US | disclosed |
| US-4367229-A | 3-Substituted-tetrahydro-pyrrolo[1,2-a]pyrimidines and pharmaceutical compositions | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1983-01-04 | — | — | US | disclosed |