Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 5/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | GRK5 | P34947 | 1/20 | 0.43 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081150 | 0.84 | HAVCR2 (0.53) | HAVCR2JAK2PAK4NTRK1LCK | |
| SCHEMBL11083967 | 0.83 | HAVCR2 (0.48) | HAVCR2JAK2PAK4NTRK1LCK | |
| SCHEMBL11088372 | 0.81 | CA12 (0.48) | HAVCR2GRIN2DGRIN3BGRIA1GRIA2 | |
| SCHEMBL11083501 | 0.81 | HAVCR2 (0.67) | HAVCR2JAK2PAK4NTRK1LCK | |
| SCHEMBL11086459 | 0.81 | JAK2 (0.50) | HAVCR2JAK2PAK4NTRK1LCK | |
| SCHEMBL11085566 | 0.81 | JAK2 (0.47) | HAVCR2JAK2PAK4NTRK1LCK | |
| SCHEMBL11082526 | 0.81 | HAVCR2 (0.66) | HAVCR2JAK2PAK4NTRK1LCK | |
| SCHEMBL11087925 | 0.81 | JAK2 (0.45) | HAVCR2JAK2PAK4NTRK1LCK | |
| SCHEMBL11089699 | 0.79 | ERCC1 (0.55) | HAVCR2JAK2PAK4NTRK1LCK | |
| SCHEMBL11089513 | 0.79 | JAK2 (0.46) | HAVCR2JAK2PAK4NTRK1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463007-A | ANTIALLERGENS | BASF AKTIENGESELLSCHAFT (DE) | 1984-07-31 | — | — | US | disclosed |