Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 2/20 | 0.55 |
| ▸ | FEN1 | P39748 | 2/20 | 0.55 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.55 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HAVCR2 | Q8TDQ0 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11172362 | 0.84 | ERCC1 (0.52) | ERCC1FEN1ERCC4DNASE1ADORA3 | |
| SCHEMBL11084519 | 0.83 | ERCC1 (0.54) | ERCC1FEN1ERCC4DNASE1ADORA3 | |
| SCHEMBL11081150 | 0.82 | HAVCR2 (0.53) | ADORA3HAVCR2HSD17B10JAK2PAK4 | |
| SCHEMBL11083967 | 0.81 | HAVCR2 (0.48) | HAVCR2HSD17B10JAK2PAK4NTRK1 | |
| SCHEMBL11088372 | 0.80 | CA12 (0.48) | ADORA3HAVCR2 | |
| SCHEMBL11083501 | 0.80 | HAVCR2 (0.67) | HAVCR2JAK2PAK4NTRK1LCK | |
| SCHEMBL11089647 | 0.79 | HAVCR2 (0.47) | HAVCR2HSD17B10JAK2PAK4NTRK1 | |
| SCHEMBL11085566 | 0.79 | JAK2 (0.47) | KDM4EALDH1A1HAVCR2HSD17B10JAK2 | |
| SCHEMBL8861987 | 0.77 | HAVCR2 (0.46) | KDM4EALDH1A1HPGDHAVCR2HSD17B10 | |
| SCHEMBL11087925 | 0.76 | JAK2 (0.45) | HAVCR2HSD17B10JAK2PAK4NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463007-A | ANTIALLERGENS | BASF AKTIENGESELLSCHAFT (DE) | 1984-07-31 | — | — | US | disclosed |