Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 6/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11091873 | 0.88 | CA1 (0.54) | CCR2GRIK1CA1CA2TTR | |
| SCHEMBL11090063 | 0.84 | CCR2 (0.60) | CCR2CA1CA2TTRALDH1A1 | |
| SCHEMBL11398514 | 0.83 | HTT (0.69) | CCR2GRIK1TTRALDH1A1HPGD | |
| SCHEMBL22868028 | 0.82 | CYP1A2 (0.53) | CCR2ALDH1A1HPGDTSHRCASP1 | |
| SCHEMBL1270519 | 0.81 | HTT (0.65) | CCR2CA1CA2ALDH1A1HPGD | |
| SCHEMBL2334304 | 0.79 | CCR2 (0.58) | CCR2ALDH1A1HPGDTSHRCASP1 | |
| SCHEMBL23372312 | 0.76 | MRGPRX4 (0.56) | CCR2GRIK1ALDH1A1HPGDKDM4E | |
| SCHEMBL641133 | 0.76 | HPGD (0.62) | CCR2TTRALDH1A1HPGDTSHR | |
| SCHEMBL3773764 | 0.76 | HSD17B10 (0.69) | CCR2GRIK1CA1CA2ALDH1A1 | |
| SCHEMBL11575054 | 0.75 | SCN8A (0.56) | GRIK1TSHRCASP1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4459306-A | ANTIDEPRESSANTS, SEDATIVES | SCIENCE UNION ET CIE (FR) | 1984-07-10 | — | — | US | disclosed |