Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | AHR | P35869 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 6/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688142 | 0.91 | ESR1 (0.62) | KMT2ANPC1RAB9ATP53NR1I2 | |
| SCHEMBL10377804 | 0.85 | ESR1 (0.57) | KMT2ALMNAESR1ESR2MAPT | |
| SCHEMBL1918507 | 0.85 | KMT2A (0.71) | KMT2ALMNAESR1ESR2MAPT | |
| SCHEMBL28994293 | 0.84 | KMT2A (0.56) | KMT2ANPC1RAB9ATP53NR1I2 | |
| SCHEMBL27686553 | 0.84 | ESR1 (0.60) | KMT2AESR1ESR2MAPTGAA | |
| SCHEMBL28822923 | 0.83 | KMT2A (0.69) | KMT2ALMNAESR1ESR2MAPT | |
| SCHEMBL10442497 | 0.82 | ESR1 (0.71) | KMT2AESR1ESR2MAPTGAA | |
| SCHEMBL19509566 | 0.81 | KMT2A (0.77) | KMT2ANPC1RAB9ATP53NR1I2 | |
| SCHEMBL8387767 | 0.81 | KMT2A (0.59) | KMT2ANPC1RAB9ATP53NR1I2 | |
| SCHEMBL31321629 | 0.81 | PRSS1 (0.63) | KMT2ANPC1RAB9ATP53NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4459306-A | ANTIDEPRESSANTS, SEDATIVES | SCIENCE UNION ET CIE (FR) | 1984-07-10 | — | — | US | disclosed |