Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | JAK2 | O60674 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688142 | 0.92 | ESR1 (0.62) | ESR1ESR2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1918507 | 0.90 | KMT2A (0.71) | ESR1ESR2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28822923 | 0.89 | KMT2A (0.69) | ESR1ESR2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10782892 | 0.88 | MAPT (0.62) | ESR1ESR2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10377804 | 0.87 | ESR1 (0.57) | ESR1ESR2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28994293 | 0.85 | KMT2A (0.56) | ESR1ESR2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9248932 | 0.84 | KMT2A (0.59) | ESR1ESR2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10442497 | 0.84 | ESR1 (0.71) | ESR1ESR2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11089698 | 0.84 | KMT2A (0.60) | ESR1ESR2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11273464 | 0.81 | KDM4E (0.64) | ESR1ESR2KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101076457-B | Pneumatic tire | BRIDGESTONE CORP | 2011-07-27 | — | — | CN | disclosed |
| CN-101076457-A | Pneumatic tire | BRIDGESTONE CORP (JP) | 2007-11-21 | — | — | CN | disclosed |