Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.46 |
| ▸ | TUBB | P07437 | 3/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089762 | 1.00 | HPGD (0.55) | HPGDNPSR1MEN1KMT2ANPC1 | |
| SCHEMBL11083270 | 0.94 | MEN1 (0.57) | HPGDNPSR1MEN1KMT2ANPC1 | |
| SCHEMBL11083267 | 0.94 | MEN1 (0.57) | HPGDNPSR1MEN1KMT2ANPC1 | |
| SCHEMBL11087995 | 0.90 | MEN1 (0.58) | HPGDNPSR1MEN1KMT2ARAB9A | |
| SCHEMBL11088011 | 0.90 | MEN1 (0.58) | HPGDNPSR1MEN1KMT2ARAB9A | |
| SCHEMBL11076704 | 0.89 | HPGD (0.57) | HPGDNPSR1MEN1KMT2ANPC1 | |
| SCHEMBL11076707 | 0.89 | HPGD (0.57) | HPGDNPSR1MEN1KMT2ANPC1 | |
| SCHEMBL11080704 | 0.89 | MEN1 (0.68) | HPGDNPSR1MEN1KMT2ANPC1 | |
| SCHEMBL11080707 | 0.89 | MEN1 (0.68) | HPGDNPSR1MEN1KMT2ANPC1 | |
| SCHEMBL11082405 | 0.88 | HPGD (0.54) | HPGDNPSR1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4428952-A | Substituted pyrrolo[2,1-b]quinazolines and pyrido[2,1-b]quinazolines useful for the treatment of or the prevention of gastrointestinal ulcers | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-01-31 | — | — | US | disclosed |