Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.52 |
| ▸ | TUBB | P07437 | 5/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11082408 | 1.00 | HPGD (0.54) | HPGDNPSR1RAB9ANPC1ALOX5 | |
| SCHEMBL11081409 | 0.94 | RAB9A (0.60) | HPGDNPSR1RAB9ANPC1ALOX5 | |
| SCHEMBL11081408 | 0.94 | RAB9A (0.60) | HPGDNPSR1RAB9ANPC1ALOX5 | |
| SCHEMBL11083165 | 0.92 | TUBB4A (0.52) | HPGDNPSR1RAB9ANPC1ALOX5 | |
| SCHEMBL11083163 | 0.92 | TUBB4A (0.52) | HPGDNPSR1RAB9ANPC1ALOX5 | |
| SCHEMBL11089272 | 0.90 | TUBB4A (0.51) | HPGDNPSR1RAB9ANPC1ALOX5 | |
| SCHEMBL11089276 | 0.90 | TUBB4A (0.51) | HPGDNPSR1RAB9ANPC1ALOX5 | |
| SCHEMBL11083073 | 0.89 | MEN1 (0.53) | HPGDNPSR1RAB9ANPC1ALOX5 | |
| SCHEMBL11083066 | 0.89 | MEN1 (0.53) | HPGDNPSR1RAB9ANPC1ALOX5 | |
| SCHEMBL11089762 | 0.88 | HPGD (0.55) | HPGDNPSR1RAB9ANPC1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4428952-A | Substituted pyrrolo[2,1-b]quinazolines and pyrido[2,1-b]quinazolines useful for the treatment of or the prevention of gastrointestinal ulcers | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-01-31 | — | — | US | disclosed |