Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089919 | 1.00 | TDP1 (0.50) | TDP1ALOX15ALDH1A1KDM4EHPGD | |
| SCHEMBL6745161 | 0.74 | TDP1 (0.59) | TDP1ALOX15ALDH1A1KDM4EHPGD | |
| SCHEMBL11041415 | 0.72 | TDP1 (0.56) | TDP1ALOX15ALDH1A1KDM4EHPGD | |
| SCHEMBL11041413 | 0.72 | TDP1 (0.56) | TDP1ALOX15ALDH1A1KDM4EHPGD | |
| Phthalic Anhydride SCHEMBL29271956 | 0.70 | TDP1 (0.88) | TDP1ALOX15ALDH1A1KDM4EHPGD | |
| Phthalic Anhydride SCHEMBL8816834 | 0.70 | TDP1 (0.88) | TDP1ALOX15ALDH1A1KDM4EHPGD | |
| Phthalic Anhydride SCHEMBL29356227 | 0.69 | TDP1 (1.00) | TDP1ALOX15ALDH1A1KDM4EHPGD | |
| Phthalic Anhydride SCHEMBL380499 | 0.69 | TDP1 (1.00) | TDP1ALOX15ALDH1A1KDM4EHPGD | |
| Phthalic Anhydride SCHEMBL220 | 0.69 | TDP1 (1.00) | TDP1ALOX15ALDH1A1KDM4EHPGD | |
| SCHEMBL11045364 | 0.68 | TDP1 (0.50) | TDP1ALOX15ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4489072-A | BACTERICIDE, ANTIBIOTIC | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-12-18 | — | — | US | disclosed |