Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041415 | 0.79 | TDP1 (0.56) | TDP1ALOX15KDM4EALDH1A1HPGD | |
| SCHEMBL11041413 | 0.79 | TDP1 (0.56) | TDP1ALOX15KDM4EALDH1A1HPGD | |
| Phthalic Anhydride SCHEMBL380499 | 0.76 | TDP1 (1.00) | TDP1ALOX15KDM4EALDH1A1HPGD | |
| Phthalic Anhydride SCHEMBL29356227 | 0.76 | TDP1 (1.00) | TDP1ALOX15KDM4EALDH1A1HPGD | |
| Phthalic Anhydride SCHEMBL220 | 0.76 | TDP1 (1.00) | TDP1ALOX15KDM4EALDH1A1HPGD | |
| SCHEMBL6749397 | 0.76 | S100A4 (0.45) | TDP1ALOX15KDM4EALDH1A1TYMS | |
| SCHEMBL11045365 | 0.74 | TDP1 (0.50) | TDP1ALOX15KDM4EALDH1A1HPGD | |
| SCHEMBL11089914 | 0.74 | TDP1 (0.50) | TDP1ALOX15KDM4EALDH1A1HPGD | |
| SCHEMBL11045364 | 0.74 | TDP1 (0.50) | TDP1ALOX15KDM4EALDH1A1HPGD | |
| SCHEMBL11089919 | 0.74 | TDP1 (0.50) | TDP1ALOX15KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1948301-A | Process for the preparation of 5-cyanophthalide starting from 5-carboxyphthalide | ADORKEM TECHNOLOGY SPA (IT) | 2007-04-18 | — | — | CN | claimed |
| CN-1948301-A | Process for the preparation of 5-cyanophthalide starting from 5-carboxyphthalide | ADORKEM TECHNOLOGY SPA (IT) | 2007-04-18 | — | — | CN | disclosed |
| EP-1281708-B1 | Process for the preparation of 5-Formylphthalide | INFOSINT SA (CH) | 2004-05-26 | — | — | EP | disclosed |