Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | TDO2 | P48775 | 3/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11779988 | 0.83 | IDO1 (0.51) | CYP3A4TDP1TP53THRBALOX15 | |
| SCHEMBL11509664 | 0.81 | TACR1 (0.36) | CYP3A4LMNAMAPTCYP1A2CYP2D6 | |
| SCHEMBL22044345 | 0.80 | TP53 (0.45) | CYP3A4TDP1TP53THRBALOX15 | |
| SCHEMBL28204747 | 0.80 | TP53 (0.45) | CYP3A4TDP1TP53THRBALOX15 | |
| SCHEMBL10389943 | 0.79 | TDP1 (0.43) | CYP3A4TDP1TP53THRBALOX15 | |
| SCHEMBL11779446 | 0.79 | ESR1 (0.44) | CYP3A4TDP1LMNAMAPTCYP1A2 | |
| SCHEMBL11092514 | 0.77 | CYP3A4 (0.50) | CYP3A4ALOX15SMN1; SMN2LMNAMAPT | |
| SCHEMBL11510215 | 0.74 | CYP3A4 (0.45) | CYP3A4LMNAMAPTCYP1A2CYP2D6 | |
| SCHEMBL11095278 | 0.74 | IDO1 (0.41) | CYP3A4TDP1TP53SMN1; SMN2ESR1 | |
| SCHEMBL8419309 | 0.74 | ESR1 (0.42) | CYP3A4LMNACYP2D6CYP2C9PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0113922-A2 | Process for the manufacture of cationic methine dyes | BAYER AG (DE) | 1984-07-25 | — | — | EP | disclosed |
| EP-0113920-A2 | Process for the manufacture of stable solutions of cationic methine dyes, and their use in spin dyeing | BAYER AG (DE) | 1984-07-25 | — | — | EP | disclosed |
| EP-0113921-A2 | Process for the manufacture of stable solutions of cationic methine dyes | BAYER AG (DE) | 1984-07-25 | — | — | EP | disclosed |
| US-3956264-A | Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |