Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092514 | 0.84 | CYP3A4 (0.50) | ESR1MAPTCYP3A4LMNACYP1A2 | |
| SCHEMBL11780210 | 0.81 | IDO1 (0.52) | ESR1MAPTCYP3A4LMNACYP1A2 | |
| SCHEMBL11089915 | 0.79 | CYP3A4 (0.41) | ESR1MAPTCYP3A4LMNACYP1A2 | |
| SCHEMBL1357301 | 0.79 | LMNA (0.41) | MAPTCYP3A4LMNACYP1A2CYP2D6 | |
| SCHEMBL11510215 | 0.76 | CYP3A4 (0.45) | ESR1MAPTCYP3A4LMNACYP1A2 | |
| SCHEMBL11500414 | 0.76 | LMNA (0.46) | ESR1LMNACYP1A2CYP2D6CHRNA7 | |
| SCHEMBL5512071 | 0.76 | LMNA (0.43) | MAPTCYP3A4LMNACYP1A2CYP2D6 | |
| SCHEMBL10683339 | 0.75 | CHRNA7 (0.52) | ESR1TDP1ALDH1A1CHRNA7MLKL | |
| SCHEMBL11100908 | 0.74 | ACHE (0.59) | MAPTCYP3A4CYP1A2TDP1ALDH1A1 | |
| SCHEMBL11779988 | 0.73 | IDO1 (0.51) | CYP3A4LMNATDP1ALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3956264-A | Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |