Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090510 | 0.87 | PDGFRB (0.55) | PDGFRBPDGFRAMAPTKDM4ENPC1 | |
| SCHEMBL11081454 | 0.86 | TP53 (0.53) | PDGFRBPDGFRAMAPTKDM4ENPC1 | |
| SCHEMBL11087968 | 0.83 | PDGFRB (0.54) | PDGFRBPDGFRAMAPTKDM4ENPC1 | |
| SCHEMBL11085404 | 0.81 | KMT2A (0.50) | MAPTKDM4ENPC1RAB9AMEN1 | |
| SCHEMBL11089591 | 0.81 | MAPT (0.47) | PDGFRBPDGFRAMAPTKDM4ENPC1 | |
| SCHEMBL11094565 | 0.81 | PDGFRB (0.50) | PDGFRBPDGFRAMAPTKDM4ENPC1 | |
| SCHEMBL11093305 | 0.81 | PDGFRB (0.46) | PDGFRBPDGFRAMAPTKDM4ENPC1 | |
| SCHEMBL11088263 | 0.79 | RHOA (0.47) | PDGFRBPDGFRAMAPTKDM4ENPC1 | |
| SCHEMBL11093811 | 0.79 | MAPT (0.56) | PDGFRBPDGFRAMAPTKDM4ENPC1 | |
| SCHEMBL11091553 | 0.79 | MAPT (0.49) | PDGFRBPDGFRAMAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460773-A | ANTITUMOR AGENTS, VIRICIDES | LION CORPORATION (JP) | 1984-07-17 | — | — | US | disclosed |