Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087968 | 0.89 | PDGFRB (0.54) | MAPTKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL11087146 | 0.88 | MAPT (0.60) | MAPTKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL11081454 | 0.83 | TP53 (0.53) | MAPTKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL11090510 | 0.83 | PDGFRB (0.55) | MAPTKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL11089081 | 0.82 | MAPT (0.59) | MAPTKDM4EHSD17B10NR3C1MEN1 | |
| SCHEMBL11088263 | 0.81 | RHOA (0.47) | MAPTKDM4EHSD17B10NR3C1MEN1 | |
| SCHEMBL11089959 | 0.81 | PDGFRB (0.43) | MAPTKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL11092383 | 0.79 | PDGFRB (0.54) | MAPTKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL11094565 | 0.79 | PDGFRB (0.50) | MAPTKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL11093305 | 0.78 | PDGFRB (0.46) | MAPTKDM4EHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460773-A | ANTITUMOR AGENTS, VIRICIDES | LION CORPORATION (JP) | 1984-07-17 | — | — | US | disclosed |