Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31623366 | 0.93 | ALDH1A1 (0.33) | ALDH1A1TDP1EPHX1 | |
| SCHEMBL31623378 | 0.93 | ALDH1A1 (0.33) | ALDH1A1TDP1EPHX1 | |
| SCHEMBL31623372 | 0.93 | ALDH1A1 (0.33) | ALDH1A1TDP1EPHX1 | |
| SCHEMBL9345701 | 0.90 | — | — | |
| SCHEMBL9345697 | 0.90 | — | — | |
| SCHEMBL23387053 | 0.87 | MEN1 (0.32) | — | |
| SCHEMBL30564566 | 0.87 | MEN1 (0.32) | — | |
| SCHEMBL30564565 | 0.87 | MEN1 (0.32) | — | |
| SCHEMBL25406202 | 0.87 | ALDH1A1 (0.34) | ALDH1A1TDP1EPHX1 | |
| SCHEMBL25406466 | 0.87 | ALDH1A1 (0.34) | ALDH1A1TDP1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486443-A | PROSTAGLANDIN-LIKE EFFECTS | BURROUGHS WELLCOME CO. (US) | 1984-12-04 | — | — | US | disclosed |
| EP-0001238-B1 | HYDANTOIN DERIVATIVES, THEIR SYNTHESIS, PHARMACEUTICAL FORMULATIONS AND INTERMEDIATES IN THEIR PREPARATION | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-07-04 | — | — | EP | disclosed |
| US-4262128-A | HAVING PROSTAGLANDIN-LIKE BIOLOGICAL PROPERTIES | BURROUGHS WELLCOME CO. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4204068-A | Nitrogen heterocycles | BURROUGHS WELLCOME CO. (US) | 1980-05-20 | — | — | US | disclosed |
| EP-0001238-A1 | Hydantoin derivatives, their synthesis, pharmaceutical formulations and intermediates in their preparation | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-04-04 | — | — | EP | disclosed |