Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 1.00 |
| ▸ | PPARA | Q07869 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | PPARG | P37231 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | PTGIR | P43119 | 7/20 | 0.64 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.64 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.64 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.64 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.64 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.57 |
| ▸ | PTGFR | P43088 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbacyclin SCHEMBL30905566 | 1.00 | PPARD (1.00) | PPARDPPARAMEN1KMT2APPARG | |
| Carbacyclin SCHEMBL13539945 | 1.00 | PPARD (1.00) | PPARDPPARAMEN1KMT2APPARG | |
| Carbacyclin SCHEMBL9643974 | 1.00 | PPARD (1.00) | PPARDPPARAMEN1KMT2APPARG | |
| Carbacyclin SCHEMBL10732794 | 1.00 | PPARD (1.00) | PPARDPPARAMEN1KMT2APPARG | |
| Carbacyclin SCHEMBL10439712 | 1.00 | PPARD (1.00) | PPARDPPARAMEN1KMT2APPARG | |
| Carbacyclin SCHEMBL24340889 | 1.00 | PPARD (1.00) | PPARDPPARAMEN1KMT2APPARG | |
| Carbacyclin SCHEMBL6172952 | 1.00 | PPARD (1.00) | PPARDPPARAMEN1KMT2APPARG | |
| Carbacyclin SCHEMBL6082848 | 1.00 | PPARD (1.00) | PPARDPPARAMEN1KMT2APPARG | |
| Carbacyclin SCHEMBL1479163 | 1.00 | PPARD (1.00) | PPARDPPARAMEN1KMT2APPARG | |
| Carbacyclin SCHEMBL28444482 | 1.00 | PPARD (1.00) | PPARDPPARAMEN1KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479966-A | 6,9-Methano-PGI2 analogues | ONO PHARMACEUTICAL COMPANY, LTD. (JP) | 1984-10-30 | — | — | US | disclosed |