SCHEMBL11090255

SCHEMBL11090255

CC(C)C[C@H](NC(=O)C(O)C(N)Cc1ccccc1)C(=O)N[C@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 15/20 0.56
NPY1R P25929 9/20 0.56
NPY5R Q15761 8/20 0.56
NPY2R P49146 5/20 0.56
LAP3 P28838 2/20 0.53
ANPEP P15144 1/20 0.53
RNPEP Q9H4A4 1/20 0.53
DNPEP Q9ULA0 1/20 0.53
KISS1R Q969F8 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11090260 1.00 NPY4R (0.56) NPY4RNPY1RNPY5RNPY2RLAP3
SCHEMBL11089233 1.00 NPY4R (0.56) NPY4RNPY1RNPY5RNPY2RLAP3
SCHEMBL11089240 1.00 NPY4R (0.56) NPY4RNPY1RNPY5RNPY2RLAP3
SCHEMBL7435448 0.92 LAP3 (0.53) NPY4RNPY1RNPY5RNPY2RLAP3
SCHEMBL21570268 0.92 LAP3 (0.53) NPY4RNPY1RNPY5RNPY2RLAP3
SCHEMBL7435439 0.92 LAP3 (0.53) NPY4RNPY1RNPY5RNPY2RLAP3
SCHEMBL29674598 0.92 LAP3 (0.53) NPY4RNPY1RNPY5RNPY2RLAP3
Hydrochloric Acid SCHEMBL7445350 0.91 LAP3 (0.52) NPY4RNPY1RNPY5RNPY2RLAP3
Hydrochloric Acid SCHEMBL7445342 0.91 LAP3 (0.52) NPY4RNPY1RNPY5RNPY2RLAP3
SCHEMBL23405252 0.89 NPY4R (0.64) NPY4RNPY1RNPY5RNPY2RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4473554-A Bestatin-related compounds as immunopotentiator ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1984-09-25 US claimed
US-4473554-A Bestatin-related compounds as immunopotentiator ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1984-09-25 US disclosed