Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 5/20 | 0.33 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | CA7 | P43166 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11626450 | 0.75 | MAPT (0.32) | MAPTGAACYP1A2CYP3A4CA12 | |
| SCHEMBL11629162 | 0.69 | CA12 (0.33) | MAPTLMNAGAASMN1; SMN2CA12 | |
| SCHEMBL10753297 | 0.69 | MAPT (0.65) | MAPTLMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10535543 | 0.69 | CA12 (0.34) | MAPTGAACA12CA1CA2 | |
| SCHEMBL11080228 | 0.69 | TDP1 (0.39) | MAPTGAAHTTSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11587509 | 0.68 | CA12 (0.35) | MAPTGAACA12CA1CA2 | |
| SCHEMBL11627741 | 0.67 | CA12 (0.36) | MAPTGAACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7156165 | 0.66 | CA12 (0.47) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL11718403 | 0.65 | ADRA2A (0.33) | MAPTGAACA12CA1CA2 | |
| SCHEMBL28503923 | 0.65 | CA12 (0.55) | MAPTLMNAGAAHTTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473374-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1984-09-25 | — | — | US | disclosed |
| US-4330291-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-05-18 | — | — | US | disclosed |