Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090585 | 1.00 | HDAC1 (0.45) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL11090583 | 1.00 | HDAC1 (0.45) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL546162 | 0.86 | MEN1 (0.47) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL29800023 | 0.85 | PTGS1 (0.48) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL4396277 | 0.85 | PTGS1 (0.48) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL11090023 | 0.83 | CYP17A1 (0.46) | CYP17A1CA1CA12CA9NAMPT | |
| SCHEMBL11090025 | 0.83 | CYP17A1 (0.46) | CYP17A1CA1CA12CA9NAMPT | |
| SCHEMBL11090020 | 0.83 | CYP17A1 (0.46) | CYP17A1CA1CA12CA9NAMPT | |
| SCHEMBL19426702 | 0.83 | IDO1 (0.49) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL12743181 | 0.83 | FADS1 (0.51) | HDAC1HDAC3HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464366-A | Cephem compounds having a terminal aminocarboxylic acid grouping and containing an azacyclyl(thio)ureido group | CIBA GEIGY CORPORATION (US) | 1984-08-07 | — | — | US | disclosed |
| EP-0031794-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1981-07-08 | — | — | EP | disclosed |