Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 2/20 | 0.67 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090906 | 0.85 | HAVCR2 (0.53) | HAVCR2GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11084782 | 0.85 | HAVCR2 (0.53) | HAVCR2GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11082274 | 0.81 | HAVCR2 (0.47) | HAVCR2GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11084193 | 0.81 | GABRP (0.64) | HAVCR2KDM4EHPGD | |
| SCHEMBL405565 | 0.80 | HAVCR2 (1.00) | HAVCR2 | |
| SCHEMBL11088234 | 0.80 | HAVCR2 (0.67) | HAVCR2CA12CA9 | |
| SCHEMBL8861987 | 0.79 | HAVCR2 (0.46) | HAVCR2GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11083967 | 0.78 | HAVCR2 (0.48) | HAVCR2GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11081150 | 0.77 | HAVCR2 (0.53) | HAVCR2 | |
| SCHEMBL11088259 | 0.77 | HAVCR2 (0.43) | HAVCR2GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463007-A | ANTIALLERGENS | BASF AKTIENGESELLSCHAFT (DE) | 1984-07-31 | — | — | US | disclosed |