⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1826501 | 0.87 | — | — | |
| SCHEMBL1825864 | 0.87 | — | — | |
| SCHEMBL1827415 | 0.80 | — | — | |
| SCHEMBL12756282 | 0.76 | — | — | |
| SCHEMBL7752813 | 0.76 | TP53 (0.31) | — | |
| SCHEMBL7752907 | 0.75 | — | — | |
| SCHEMBL6699147 | 0.75 | — | — | |
| SCHEMBL6252507 | 0.70 | — | — | |
| SCHEMBL5677487 | 0.70 | — | — | |
| SCHEMBL6463410 | 0.69 | CDC25B (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4485236-A | NUCLEOPHILIC GROUP SUBSTITUTION; CROSSLINKED POLYAMIDE RESIN SYSTEMS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-11-27 | — | — | US | claimed |
| EP-0105665-A1 | Azlactone-functional compounds and curable compositions containing same | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-04-18 | — | — | EP | claimed |
| US-4485236-A | NUCLEOPHILIC GROUP SUBSTITUTION; CROSSLINKED POLYAMIDE RESIN SYSTEMS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-11-27 | — | — | US | disclosed |