⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252507 | 0.89 | — | — | |
| SCHEMBL7752813 | 0.87 | TP53 (0.31) | — | |
| SCHEMBL12756282 | 0.83 | — | — | |
| SCHEMBL13783711 | 0.83 | — | — | |
| SCHEMBL6699147 | 0.82 | — | — | |
| SCHEMBL7752907 | 0.82 | — | — | |
| SCHEMBL6698827 | 0.79 | TP53 (0.31) | — | |
| SCHEMBL1825864 | 0.77 | — | — | |
| SCHEMBL8628125 | 0.77 | TP53 (0.30) | — | |
| SCHEMBL6463410 | 0.76 | CDC25B (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2909185-A1 | MULTIFUNCTIONAL COUPLING REAGENTS HAVING AN AZLACTONE FUNCTION | CNRS (Centre National de la Recherche Scientifique) (FR) | 2015-08-26 | — | — | EP | disclosed |
| WO-2014060357-A1 | MULTIFUNCTIONAL COUPLING REAGENTS HAVING AN AZLACTONE FUNCTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-04-24 | — | — | WO | disclosed |
| EP-1622952-A1 | AZLACTONE CHAIN TRANSFER AGENTS FOR RADICAL POLYMERIZATION | 3M Innovative Properties Company (US) | 2006-02-08 | — | — | EP | disclosed |
| EP-1620482-A1 | RING-OPENED AZLACTONE CHAIN TRANSFER AGENTS FOR RADICAL POLYMERIZATION | 3M Innovative Properties Company (US) | 2006-02-01 | — | — | EP | disclosed |
| EP-1569967-A1 | AZLACTONE INITIATORS FOR ATOM TRANSFER RADICAL POLYMERIZATION | 3M Innovative Properties Company (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004099275-A1 | AZLACTONE CHAIN TRANSFER AGENTS FOR RADICAL POLYMERIZATION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-11-18 | — | — | WO | disclosed |
| WO-2004099276-A1 | RING-OPENED AZLACTONE CHAIN TRANSFER AGENTS FOR RADICAL POLYMERIZATION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-11-18 | — | — | WO | disclosed |
| WO-2004052943-A1 | AZLACTONE INITIATORS FOR ATOM TRANSFER RADICAL POLYMERIZATION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-06-24 | — | — | WO | disclosed |