Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.62 |
| ▸ | IL1RN | P18510 | 4/20 | 0.58 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.56 |
| ▸ | LAP3 | P28838 | 2/20 | 0.55 |
| ▸ | ANPEP | P15144 | 1/20 | 0.55 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.55 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 5/20 | 0.54 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.54 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092247 | 1.00 | ERAP2 (0.62) | ERAP2IL1RNERAP1LAP3ANPEP | |
| SCHEMBL11095143 | 0.91 | MME (0.63) | ERAP2IL1RNERAP1LAP3ANPEP | |
| SCHEMBL11090040 | 0.91 | MME (0.63) | ERAP2IL1RNERAP1LAP3ANPEP | |
| SCHEMBL11095200 | 0.91 | MME (0.63) | ERAP2IL1RNERAP1LAP3ANPEP | |
| SCHEMBL11090048 | 0.91 | MME (0.63) | ERAP2IL1RNERAP1LAP3ANPEP | |
| SCHEMBL11412768 | 0.91 | NAALAD2 (0.63) | ERAP2LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL11412781 | 0.91 | NAALAD2 (0.63) | ERAP2LAP3ANPEPRNPEPDNPEP | |
| Ubenimex SCHEMBL17889224 | 0.89 | MME (0.66) | LAP3ANPEPRNPEPDNPEPMME | |
| Ubenimex SCHEMBL22632072 | 0.89 | MME (0.66) | LAP3ANPEPRNPEPDNPEPMME | |
| Ubenimex SCHEMBL25971 | 0.89 | MME (0.66) | LAP3ANPEPRNPEPDNPEPMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4370318-A | Bestatin-related compounds as immunopotentiator | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1983-01-25 | — | — | US | claimed |
| US-4473554-A | Bestatin-related compounds as immunopotentiator | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1984-09-25 | — | — | US | disclosed |
| US-4370318-A | Bestatin-related compounds as immunopotentiator | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1983-01-25 | — | — | US | disclosed |