Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 4/20 | 0.63 |
| ▸ | LAP3 | P28838 | 2/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.54 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.54 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | CPA3 | P15088 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 2/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11412781 | 1.00 | NAALAD2 (0.63) | NAALAD2LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL11414804 | 0.91 | LAP3 (0.53) | NAALAD2LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL11414794 | 0.91 | LAP3 (0.53) | NAALAD2LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL11092241 | 0.91 | ERAP2 (0.62) | NAALAD2LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL11092247 | 0.91 | ERAP2 (0.62) | NAALAD2LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL11414321 | 0.88 | MME (0.61) | LAP3ANPEPRNPEPDNPEPMME | |
| SCHEMBL11414316 | 0.88 | MME (0.61) | LAP3ANPEPRNPEPDNPEPMME | |
| SCHEMBL11415082 | 0.87 | LAP3 (0.57) | LAP3ANPEPRNPEPDNPEPMME | |
| SCHEMBL5812584 | 0.87 | LAP3 (0.57) | LAP3ANPEPRNPEPDNPEPMME | |
| SCHEMBL5812579 | 0.87 | LAP3 (0.57) | LAP3ANPEPRNPEPDNPEPMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4240975-A | USED AS ENZYME INHIBITOR, ANTIFERTILITY AGENT, AND ENHANCES THE ANTITUMOR EFFECT OF BLEOMYCIN | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1980-12-23 | — | — | US | disclosed |
| US-4189604-A | PEPTIDASE ENZYME INHIBITORS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1980-02-19 | — | — | US | disclosed |