SCHEMBL11092573

SCHEMBL11092573

O=P(O)(Oc1ccc(Br)c(Br)c1Br)Oc1c(Br)c(Br)c(Br)c(Br)c1Br

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 3/20 0.37
INPP5A Q14642 3/20 0.37
AKT1 P31749 1/20 0.37
ALOX15 P16050 2/20 0.33
ALOX12 P18054 1/20 0.33
GPR84 Q9NQS5 1/20 0.32
AKR1B1 P15121 1/20 0.32
INPP5B P32019 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30024065 0.80 INPPL1 (0.54) INPPL1INPP5AAKT1INPP5BTDP1
SCHEMBL5567357 0.80 INPPL1 (0.54) INPPL1INPP5AAKT1INPP5BTDP1
SCHEMBL11572482 0.79 INPPL1 (0.32) INPPL1INPP5AAKT1INPP5B
SCHEMBL4838825 0.77 INPPL1 (0.32) INPPL1INPP5AAKT1
SCHEMBL160182 0.75 TDP1 (0.34) INPPL1INPP5AAKT1TDP1
SCHEMBL3871539 0.74 INPPL1 (0.44) INPPL1INPP5AAKT1GPR84INPP5B
SCHEMBL165195 0.73 TDP1 (0.46) ALOX15ALOX12AKR1B1TDP1
SCHEMBL9780376 0.71 TDP1 (0.44) ALOX15ALOX12AKR1B1TDP1
SCHEMBL6687355 0.71 INPPL1 (0.36) INPPL1INPP5AAKT1INPP5B
SCHEMBL25229878 0.71 TDP1 (0.31) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4451638-A ALKALI METAL SILICATE POLYCARBOXYLIC ACID AND POLYOL; COATINGS, PAINTS, POLYURETHANES BLOUNT DAVID H 1984-05-29 US disclosed
US-RE31340-E Process for the production of poly (polyisocyanate-polyol-alkali metal silicate) solid Blount, David H. (US) 1983-08-09 US disclosed
US-4383049-A POLYURETHANES BLOUNT DAVID H 1983-05-10 US disclosed
US-4380592-A Process for the production of polyhydroxy lignin-cellulose silicate polymer BLOUNT DAVID H (US) 1983-04-19 US disclosed
US-4378441-A Process for the production of polyester silicate resinous products BLOUNT DAVID H 1983-03-29 US disclosed
US-4377674-A POLYURETHANES; FOAMS; COPOLYMERS; INSULATION BLOUNT DAVID H 1983-03-22 US disclosed
US-4377646-A REACTING AN EPOXY COMPOUND, SILICIC ACID, AND A POLYISOCYANATE USING A LEWIS ACID CATALYST; POLYURETHANES; INSULATION BLOUNT DAVID H 1983-03-22 US disclosed
US-4377659-A MOLDING POWDER, COATINGS BLOUNT DAVID H 1983-03-22 US disclosed
US-4376171-A LIGNIN, CELLULOSE, POLYURETHANE FOAM BLOUNT DAVID H 1983-03-08 US disclosed
US-4374976-A Process for the production of polyamide silicate resinous products BLOUNT DAVID H 1983-02-22 US disclosed
US-4281110-A Process for the production of broken down lignin-cellulose silicate copolymers BLOUNT DAVID H 1981-07-28 US disclosed
US-4273908-A Process for the production of poly (polyisocyanate-polyol-alkali metal silicate solid BLOUNT DAVID H 1981-06-16 US disclosed
EP-0026204-A1 PROCESS FOR THE PRODUCTION OF ALKALI METAL-CELLULOSE-SILICATES AND THEIR REACTION PRODUCTS BLOUNT, David H. (US) 1981-04-08 EP disclosed
US-4260696-A Process for the production of polyurethane silicate foams and resinous products utilizing aldehyde-broken down alkali metal cellulose silicate polymer BLOUNT DAVID H 1981-04-07 US disclosed
US-4252934-A MOLDING MATERIALS; PROTECTIVE COATINGS; FOAMS; POLYURETHANES BLOUNT DAVID H 1981-02-24 US disclosed
US-4247657-A POLYISOCYANATE BLOUNT DAVID 1981-01-27 US disclosed
US-4243757-A USING CELLULOSE-CONTAINING PLANTS; POLYURETHANE AND POLYETHERURETHANE FOAMS BLOUNT DAVID H 1981-01-06 US disclosed
US-4241194-A AMINO RESIN OR PHENOLIC RESIN PRODUCTS ARE USEFUL FOR THERMAL OR SOUND INSULATING BUILDING MATERIALS BLOUNT DAVID H 1980-12-23 US disclosed
WO-1980002142-A1 PROCESS FOR THE PRODUCTION OF ALKALI METAL-CELLULOSE-SILICATES AND THEIR REACTION PRODUCTS BLOUNT D (US) 1980-10-16 WO disclosed
US-4220757-A Process for the production of alkali metal-cellulose-silicates and their reaction products BLOUNT DAVID H 1980-09-02 US disclosed