SCHEMBL6687355

SCHEMBL6687355

O=P(O)(O)OP(=O)(Oc1ccc(Br)c(Br)c1Br)OP(=O)(Oc1ccc(Br)c(Br)c1Br)Oc1ccc(Br)c(Br)c1Br

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 4/20 0.36
INPP5A Q14642 4/20 0.36
AKT1 P31749 1/20 0.36
INPP5B P32019 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5567357 0.82 INPPL1 (0.54) INPPL1INPP5AAKT1INPP5B
SCHEMBL30024065 0.82 INPPL1 (0.54) INPPL1INPP5AAKT1INPP5B
SCHEMBL4838825 0.82 INPPL1 (0.32) INPPL1INPP5AAKT1
SCHEMBL160182 0.82 TDP1 (0.34) INPPL1INPP5AAKT1
SCHEMBL25229878 0.77 TDP1 (0.31)
SCHEMBL9505666 0.71 SRC (0.41)
SCHEMBL9014853 0.71 SRC (0.41)
SCHEMBL11092573 0.71 INPPL1 (0.37) INPPL1INPP5AAKT1INPP5B
SCHEMBL9711439 0.69 MAPK1 (0.41) INPPL1INPP5A
SCHEMBL11290224 0.66 LMNA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5681875-A MOLDING MATERIALS; IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1997-10-28 US claimed
WO-2004078445-A2 THICK THERMOPLASTIC COMPOSITES KOMPOSITEC, LLC (US) 2004-09-16 WO disclosed
US-20040175563-A1 Thick thermoplastic composites OKERSON C ALBERT (US) 2004-09-09 US disclosed
US-20020004542-A1 Ignition resistant monovinylidene aromatic copolymer composition OGOE SAMUEL A (US) 2002-01-10 US disclosed
EP-0708133-B1 Process for making flame retardant thermoplastic compositions GEN ELECTRIC (US) 2001-01-03 EP disclosed
US-5799870-A Thermoplastic railroad tie DEMER CORPORATION (US) 1998-09-01 US disclosed
US-5741854-A IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1998-04-21 US disclosed
US-5719209-A PREBLENDING A LUBRICANT WITH TETRAFLUOROETHYLENE POLYMER; STORAGE STABILITY GENERAL ELECTRIC COMPANY (US) 1998-02-17 US disclosed
US-5681875-A MOLDING MATERIALS; IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1997-10-28 US disclosed
EP-0723992-A1 Flame retardant high impact polystyrene composition GENERAL ELECTRIC COMPANY (US) 1996-07-31 EP disclosed
US-5539036-A ABS TERPOLYMER, BROMINATED COMPOUND, ANTIMONY OXIDE, PTFE DRIP SUPPRESSANT, HOUSINGS FOR OFFICE MACHINES GENERAL ELECTRIC COMPANY (US) 1996-07-23 US disclosed
EP-0708133-A1 Tetrafluoroethylene polymer compositions and process for making flame retardant thermoplastic compositions utilizing the same GENERAL ELECTRIC COMPANY (US) 1996-04-24 EP disclosed