Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.63 |
| ▸ | CD38 | P28907 | 1/20 | 0.62 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.56 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | FADS1 | O60427 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11088198 | 0.99 | EGFR (0.62) | EGFRCD38TTBK1TTBK2SRC | |
| SCHEMBL11091920 | 0.88 | TTBK1 (0.59) | EGFRCD38TTBK1TTBK2SRC | |
| Hydrochloric Acid SCHEMBL11089555 | 0.87 | TTBK1 (0.58) | EGFRCD38TTBK1TTBK2SRC | |
| SCHEMBL8907064 | 0.86 | EGFR (0.60) | EGFRCD38SRCCYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11093777 | 0.85 | EGFR (0.59) | EGFRCD38SRCCYP1A2CYP2D6 | |
| SCHEMBL9017045 | 0.84 | TTBK1 (0.61) | EGFRCD38TTBK1TTBK2DYRK1A | |
| SCHEMBL11084317 | 0.82 | HTT (0.75) | EGFRSRCCYP1A2CYP2D6KDM4E | |
| SCHEMBL5568397 | 0.82 | EGFR (0.68) | EGFRSRCDYRK1AALDH1A1FADS1 | |
| SCHEMBL8870666 | 0.82 | EGFR (0.81) | EGFRDYRK1ACYP1A2CYP2D6KDM4E | |
| Hydrochloric Acid SCHEMBL11085643 | 0.81 | HTT (0.73) | EGFRSRCCYP1A2CYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464375-A | ANALGESIC, ANTIINFLAMMATORY | SANKYO CO., LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| US-4322420-A | Method of using 4-anilinoquinazoline derivatives as analgesic and anti-inflammatory agents | SANKYO COMPANY LIMITED (JP) | 1982-03-30 | — | — | US | disclosed |