Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 13/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 13/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080437 | 0.95 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DPGR | |
| SCHEMBL10647307 | 0.90 | PGR (0.49) | PDE4APDE4BPDE4CPDE4DPGR | |
| SCHEMBL11092621 | 0.89 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DGPR119 | |
| SCHEMBL11091612 | 0.86 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DGPR119 | |
| SCHEMBL11090158 | 0.86 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DGPR119 | |
| SCHEMBL11091636 | 0.84 | PGR (0.52) | PDE4APDE4BPDE4CPDE4DPGR | |
| SCHEMBL11088031 | 0.84 | PDE3B (0.50) | PDE4APDE4BPDE4CPDE4DGPR119 | |
| SCHEMBL11092476 | 0.83 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DGPR119 | |
| SCHEMBL11086407 | 0.83 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DPGR | |
| SCHEMBL11084163 | 0.83 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474785-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | BASF AKTIENGESELLSCHAFT (DE) | 1984-10-02 | — | — | US | disclosed |