Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 8/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | PAH | P00439 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10801475 | 0.99 | NOS1 (0.42) | NOS1USP2CASP7HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL10618545 | 0.83 | NOS1 (0.54) | NOS1USP2CASP7HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL10615692 | 0.83 | NOS1 (0.60) | NOS1USP2CASP7HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL10615706 | 0.83 | KDM4E (0.42) | NOS1USP2CASP7HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL10615647 | 0.83 | NOS1 (0.61) | NOS1USP2CASP7HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL10616936 | 0.81 | NOS1 (0.41) | NOS1USP2CASP7HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL10798798 | 0.81 | NOS1 (0.41) | NOS1USP2CASP7HSD17B10KDM4E | |
| SCHEMBL10802425 | 0.80 | NOS1 (0.46) | NOS1USP2CASP7HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL10618021 | 0.79 | NOS1 (0.46) | NOS1USP2CASP7HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL10618018 | 0.79 | NOS1 (0.43) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108890-A2 | Pharmaceutically active pteridine derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-05-23 | — | — | EP | disclosed |