Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | CYP3A5 | P20815 | 3/20 | 0.48 |
| ▸ | FDPS | P14324 | 4/20 | 0.44 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095244 | 0.84 | CYP19A1 (0.50) | CYP19A1CYP3A4CYP3A5KMT2A | |
| SCHEMBL11098696 | 0.81 | CYP11B1 (0.44) | CYP3A4CYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL11094188 | 0.79 | CYP19A1 (0.50) | CYP19A1CYP3A4CYP3A5KMT2A | |
| SCHEMBL11093858 | 0.74 | CYP3A4 (0.62) | CYP19A1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10472521 | 0.74 | CYP19A1 (0.47) | CYP19A1CYP3A4CYP3A5KCNA5 | |
| SCHEMBL11628668 | 0.74 | CYP19A1 (0.64) | CYP19A1CYP3A4CYP3A5KCNA5 | |
| SCHEMBL10463875 | 0.72 | CYP11B1 (0.51) | CYP19A1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10724839 | 0.72 | CYP19A1 (0.50) | CYP19A1CYP3A4CYP3A5KMT2A | |
| SCHEMBL10369963 | 0.71 | CYP19A1 (0.41) | CYP19A1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14349293 | 0.71 | CYP1A2 (0.49) | CYP3A4CYP1A2CYP2C9CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109299-A2 | 1,1-Disubstituted-2-heterocyclic ethanol derivatives | ELI LILLY AND COMPANY (US) | 1984-05-23 | — | — | EP | claimed |
| EP-0109299-A2 | 1,1-Disubstituted-2-heterocyclic ethanol derivatives | ELI LILLY AND COMPANY (US) | 1984-05-23 | — | — | EP | disclosed |