Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | UBE2M | P61081 | 1/20 | 0.49 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087315 | 0.88 | SLC2A1 (0.46) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11089213 | 0.86 | MAPT (0.52) | MAPTMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL11092543 | 0.82 | MAPT (0.44) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11091320 | 0.82 | SLC2A1 (0.46) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11093839 | 0.81 | CCKBR (0.48) | MEN1KMT2ASMN1; SMN2MAPK1POLB | |
| SCHEMBL11097174 | 0.76 | CCKBR (0.47) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11088647 | 0.73 | CCKBR (0.47) | LMNAMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL11085822 | 0.72 | POLB (0.53) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11165997 | 0.71 | BRD4 (0.43) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11487659 | 0.71 | TP53 (0.53) | MAPTMEN1KMT2ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055917-B1 | NEW BENZOTHIAZINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-21 | — | — | EP | disclosed |
| US-4397849-A | AUTOIMMUNE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-08-09 | — | — | US | disclosed |
| EP-0055917-A1 | New benzothiazine derivatives, processes for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-07-14 | — | — | EP | disclosed |