Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11201136 | 0.89 | CA12 (0.39) | MAPTHTTALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL11160842 | 0.87 | KMT2A (0.37) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL11122670 | 0.86 | SMN1; SMN2 (0.43) | MAPTHTTALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL11154277 | 0.84 | MEN1 (0.36) | MAPTHTTSMN1; SMN2CA12CA1 | |
| SCHEMBL10370951 | 0.84 | CA12 (0.42) | MAPTHTTALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL11156277 | 0.81 | KMT2A (0.46) | MAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL11156567 | 0.81 | TRIM24 (0.40) | MAPTHTTALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL11158224 | 0.81 | CA12 (0.38) | MAPTHTTSMN1; SMN2CA12CA1 | |
| SCHEMBL11087998 | 0.81 | KMT2A (0.40) | MAPTHTTALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL10373647 | 0.81 | CA12 (0.46) | MAPTHTTALDH1A1SMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107261-A2 | (2-((Nitropyridinyl)amino)phenyl)arylmethanones and salts, their use in medicine, pharmaceutical compositions containing them and their use in the preparation of (2-((aminopyridinyl)amino)phenyl)arylmethanones and pyrido(1,4)benzodiazepines | A.H. ROBINS COMPANY, INCORPORATED (US) | 1984-05-02 | — | — | EP | disclosed |