Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11160842 | 0.90 | KMT2A (0.37) | CA12CA1CA2CA9MAPK14 | |
| SCHEMBL10370951 | 0.90 | CA12 (0.42) | CA12CA1CA2CA9MAPK14 | |
| SCHEMBL11095322 | 0.89 | MAPT (0.43) | CA12CA1CA2CA9MAPK14 | |
| SCHEMBL11122670 | 0.89 | SMN1; SMN2 (0.43) | CA12CA1CA2CA9MAPK14 | |
| SCHEMBL11154277 | 0.87 | MEN1 (0.36) | CA12CA1CA2CA9MAPK14 | |
| SCHEMBL11156567 | 0.86 | TRIM24 (0.40) | CA12CA1CA2CA9MAPK14 | |
| SCHEMBL11158224 | 0.86 | CA12 (0.38) | CA12CA1CA2CA9MAPK14 | |
| SCHEMBL11087998 | 0.86 | KMT2A (0.40) | CA12CA1CA2CA9MAPK14 | |
| SCHEMBL11176334 | 0.86 | TRIM24 (0.36) | CA12CA1CA2CA9MAPK14 | |
| SCHEMBL11180700 | 0.86 | HPGD (0.37) | CA12CA1CA2CA9MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0076017-A2 | Phenyl substituted pyrido(1,4)benzodiazepines and intermediates therefor | A.H. ROBINS COMPANY, INCORPORATED (US) | 1983-04-06 | — | — | EP | claimed |