Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CD44 | P16070 | 1/20 | 0.33 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3138636 | 0.76 | TSHR (0.49) | MEN1KMT2ACYP1A2GRM1TDP1 | |
| SCHEMBL11091003 | 0.76 | HTR2A (0.45) | LMNAMEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL11097763 | 0.73 | HTR2B (0.38) | MCL1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL11872401 | 0.69 | CA12 (0.45) | LMNACA12CA1CA2CA9 | |
| SCHEMBL12297358 | 0.69 | LMNA (0.59) | LMNACA12CA1CA2CA9 | |
| SCHEMBL5842683 | 0.68 | ATM (0.42) | LMNAMCL1MEN1KMT2ATDP1 | |
| SCHEMBL5966930 | 0.68 | CYP3A4 (0.47) | CA1CA2MEN1KMT2ACYP1A2 | |
| SCHEMBL9159628 | 0.68 | TSHR (0.47) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3151828 | 0.67 | FFAR4 (0.40) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL11091138 | 0.67 | ACP3 (0.46) | MEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461911-A | FROM THIOGLYCOLIC ACID AND AN ARYLDIAZONIUM SALT, COPPER SALT, ACID MEDIUM | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-24 | — | — | US | disclosed |