Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.62 |
| ▸ | RELA | Q04206 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095416 | 1.00 | MAPT (0.68) | MAPTNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL31322028 | 1.00 | MAPT (0.68) | MAPTNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL28340400 | 0.85 | MAPT (0.62) | MAPTNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL14601553 | 0.81 | ALDH1A1 (0.63) | MAPTNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL15404139 | 0.81 | MAPT (1.00) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL7997434 | 0.81 | MAPT (1.00) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL10057828 | 0.81 | ALDH1A1 (0.66) | MAPTNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL7075198 | 0.81 | ALDH1A1 (0.65) | MAPTNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL19243173 | 0.81 | ALDH1A1 (0.65) | MAPTNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL108665 | 0.81 | MAPT (0.79) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483868-A | ANTIULCER AGENTS ANTISECRETORY AGENTS | ROUSSEL UCLAF (FR) | 1984-11-20 | — | — | US | claimed |
| US-4483868-A | ANTIULCER AGENTS ANTISECRETORY AGENTS | ROUSSEL UCLAF (FR) | 1984-11-20 | — | — | US | disclosed |