Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095687 | 1.00 | KCNH2 (0.44) | KCNH2OPRK1OPRM1OPRD1SLC6A4 | |
| Hydrochloric Acid SCHEMBL11096230 | 0.99 | KCNH2 (0.43) | KCNH2OPRK1OPRM1OPRD1SLC6A4 | |
| SCHEMBL11095893 | 0.83 | TSHR (0.44) | KCNH2OPRK1OPRM1SLC6A4SLC6A3 | |
| SCHEMBL11097065 | 0.79 | SLC6A4 (0.48) | KCNH2OPRK1OPRM1OPRD1SLC6A4 | |
| SCHEMBL11095157 | 0.79 | SLC6A4 (0.48) | KCNH2OPRK1OPRM1OPRD1SLC6A4 | |
| Hydrochloric Acid SCHEMBL11093298 | 0.78 | CHRM2 (0.49) | KCNH2OPRK1OPRM1OPRD1SLC6A4 | |
| SCHEMBL10721025 | 0.76 | HRH3 (0.49) | KCNH2OPRK1OPRM1OPRD1SLC6A4 | |
| SCHEMBL11096355 | 0.76 | KCNH2 (0.59) | KCNH2OPRK1OPRM1OPRD1L3MBTL1 | |
| SCHEMBL20483452 | 0.75 | CHRM2 (0.64) | KCNH2OPRK1OPRM1HRH3CHRM2 | |
| Hydrochloric Acid SCHEMBL11094804 | 0.75 | KCNH2 (0.57) | KCNH2OPRK1OPRM1OPRD1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031219-B1 | ANILINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1984-03-07 | — | — | EP | disclosed |
| US-4350691-A | ANTIEMETICS | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |
| EP-0031219-A1 | Aniline derivatives | BEECHAM GROUP PLC (GB) | 1981-07-01 | — | — | EP | disclosed |