Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11094804 | 0.98 | KCNH2 (0.57) | KCNH2OPRK1OPRM1OPRD1L3MBTL1 | |
| SCHEMBL8947193 | 0.82 | NR1H2 (0.54) | KCNH2OPRK1OPRM1OPRD1L3MBTL1 | |
| SCHEMBL3971681 | 0.82 | ALDH1A1 (0.56) | KCNH2OPRK1OPRM1OPRD1L3MBTL1 | |
| SCHEMBL12794645 | 0.82 | ALDH1A1 (0.56) | KCNH2OPRK1OPRM1OPRD1L3MBTL1 | |
| SCHEMBL31488579 | 0.81 | NR1H2 (0.45) | KCNH2OPRK1OPRM1OPRD1LMNA | |
| SCHEMBL17506126 | 0.81 | NR1H2 (0.45) | KCNH2OPRK1OPRM1OPRD1LMNA | |
| SCHEMBL7371335 | 0.81 | LMNA (0.56) | KCNH2OPRK1OPRM1OPRD1L3MBTL1 | |
| SCHEMBL11094118 | 0.81 | LMNA (0.56) | KCNH2OPRK1OPRM1OPRD1L3MBTL1 | |
| SCHEMBL5354509 | 0.81 | OPRK1 (0.55) | KCNH2OPRK1OPRM1OPRD1L3MBTL1 | |
| SCHEMBL17506127 | 0.80 | NR1H2 (0.44) | KCNH2OPRK1OPRM1OPRD1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031219-B1 | ANILINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1984-03-07 | — | — | EP | disclosed |
| US-4350691-A | ANTIEMETICS | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |
| EP-0031219-A1 | Aniline derivatives | BEECHAM GROUP PLC (GB) | 1981-07-01 | — | — | EP | disclosed |